Finer-Moore, Janet : rechercher sur Z-Library

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1

Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion

Rosenberg, Oren S., Dovala, Dustin, Li, Xueming, Connolly, Lynn, Bendebury, Anastasia, Finer-Moore, Janet, Holton, James, Cheng, Yifan, Stroud, Robert M., Cox, Jeffery S.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 3.39 MB

english, 2015

2

A Single Mutation Traps a Half-Sites Reactive Enzyme in Midstream, Explaining Asymmetry in Hydride Transfer

Finer-Moore, Janet S., Lee, Tom T., Stroud, Robert M.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 6.72 MB

english, 2018

3

Emblide, a new polyfunctional cembranolide from the soft coral sarcophyton glaucum

John A. Toth, B. Jay Burreson, Paul J. Scheuer, Janet Finer-Moore, Jon Clardy

Journal:

Année:

1980

Langue:

english

Fichier:

PDF, 242 KB

english, 1980

4

The structure of acumycin: A 16-membered ring macrolide antibiotic

Jon Clardy, Janet Finer-Moore, Larry Weiler, Don C. Wiley

Journal:

Année:

1981

Langue:

english

Fichier:

PDF, 534 KB

english, 1981

5

An alumina catalyzed addition of secondary amines to exocyclic α,β-unsaturated ketones

S.William Pelletier, Atanas P. Venkov, Janet Finer-Moore, Naresh V. Mody

Journal:

Tetrahedron Letters

Année:

1980

Langue:

english

Fichier:

PDF, 191 KB

english, 1980

6

An unusual oxidation of an NCH3 group to an NCHO group by osmium tetroxide

S.William Pelletier, Haridutt K. Desai, Janet Finer-Moore, Naresh V. Mody

Journal:

Tetrahedron Letters

Année:

1982

Langue:

english

Fichier:

PDF, 225 KB

english, 1982

7

Predicting and harnessing protein flexibility in the design of species-specific inhibitors of thymidylate synthase

Timothy A Fritz, Donatella Tondi, Janet S Finer-Moore, M.Paola Costi, Robert M Stroud

Journal:

Chemistry & Biology

Année:

2001

Langue:

english

Fichier:

PDF, 811 KB

english, 2001

8

Structural and functional basis for RNA cleavage by Ire1

Alexei V Korennykh, Andrei A Korostelev, Pascal F Egea, Janet Finer-Moore, Robert M Stroud, Chao Zhang, Kevan M Shokat, Peter Walter

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2011

9

Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1

Alexei V Korennykh, Pascal F Egea, Andrei A Korostelev, Janet Finer-Moore, Robert M Stroud, Chao Zhang, Kevan M Shokat, Peter Walter

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2011

10

Plastic adaptation toward mutations in proteins: Structural comparison of thymidylate synthases

Kathy M. Perry, Eric B. Fauman, Janet S. Finer-Moore, William R. Montfort, Gladys F. Maley, Frank Maley, Robert M. Stroud

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1990

Langue:

english

Fichier:

PDF, 2.38 MB

english, 1990

11

Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction

Janet S. Finer-Moore, Anthony A. Kossiakoff, James H. Hurley, Thomas Earnest, Dr. Robert M. Stroud

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1992

Langue:

english

Fichier:

PDF, 1.98 MB

english, 1992

12

Δ9(15)-Africanene, a new sesquiterpene hydrocarbon from the soft coralSinularia erecta

Y. Kashman, M. Bodner, Janet S. Finer-Moore, J. Clardy

Journal:

Cellular and Molecular Life Sciences

Année:

1980

Langue:

english

Fichier:

PDF, 206 KB

english, 1980

13

The structure and absolute configuration of heterophylloidine

S.William Pelletier, Naresh V. Mody, Janet Finer-Moore, Haridutt K. Desai, H.S. Puri

Journal:

Tetrahedron Letters

Année:

1981

Langue:

english

Fichier:

PDF, 129 KB

english, 1981

14

10.1038/26773

Syed, Rashid S., Reid, Scott W., Li, Cuiwei, Cheetham, Janet C., Aoki, Kenneth H., Liu, Beishan, Zhan, Hangjun, Osslund, Timothy D., Chirino, Arthur J., Zhang, Jiandong, Finer-Moore, Janet, Elliott, S

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 521 KB

english, 1998

15

10.1038/35422

Katz, Bradley A., Clark, James M., Finer-Moore, Janet S., Jenkins, Thomas E., Johnson, Charles R., Ross, Michael J., Luong, Christine, Moore, William R., Stroud, Robert M.

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 428 KB

english, 1998

16

The unfolded protein response signals through high-order assembly of Ire1

Korennykh, Alexei V., Egea, Pascal F., Korostelev, Andrei A., Finer-Moore, Janet, Zhang, Chao, Shokat, Kevan M., Stroud, Robert M., Walter, Peter

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2008

17

Partitioning Roles of Side Chains in Affinity, Orientation, and Catalysis with Structures for Mutant Complexes: Asparagine-229 in Thymidylate Synthase†,‡

Finer-Moore, Janet S., Liu, Lu, Schafmeister, Christian E., Birdsall, David L., Mau, Ted, Santi, Daniel V., Stroud, Robert M.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 764 KB

english, 1996

18

Refined Structures of Substrate-bound and Phosphate-bound Thymidylate Synthase from Lactobacillus casei

Janet Finer-Moore, Eric B. Fauman, Paul G. Foster, Kathy M. Perry, Daniel V. Santi, Robert M. Stroud

Journal:

Journal of Molecular Biology

Année:

1993

Fichier:

PDF, 939 KB

1993

19

Entropy in Bi-substrate Enzymes: Proposed Role of an Alternate Site in Chaperoning Substrate into, and Products out of, Thymidylate Synthase

David L. Birdsall, Janet Finer-Moore, Robert M. Stroud

Journal:

Journal of Molecular Biology

Année:

1996

Langue:

english

Fichier:

PDF, 1.61 MB

english, 1996

20

Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase

Janet S Finer-Moore, Lu Liu, David L Birdsall, Rachel Brem, Javier Apfeld, Daniel V Santi, Robert M Stroud

Journal:

Journal of Molecular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 739 KB

english, 1998

21

Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer

Christopher L. Reyes, Carleton R. Sage, Earl E. Rutenber, Robert M. Nissen, Janet S. Finer-Moore, Robert M. Stroud

Journal:

Journal of Molecular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 2.11 MB

english, 1998

22

Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases

Peter H Sayre, Janet S Finer-Moore, Timothy A Fritz, Donna Biermann, Susan B Gates, Warren C MacKellar, Vinod F Patel, Robert M Stroud

Journal:

Journal of Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 749 KB

english, 2001

23

The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE

Hu Pan, Joseph D. Ho, Robert M. Stroud, Janet Finer-Moore

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 2.68 MB

english, 2007

24

Crystal Structure of an RluF–RNA Complex: A Base-Pair Rearrangement Is the Key to Selectivity of RluF for U2604 of the Ribosome

Akram Alian, Andrew DeGiovanni, Sarah L. Griner, Janet S. Finer-Moore, Robert M. Stroud

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2009

25

Inhibitor of Ovarian Cancer Cells Growth by Virtual Screening: A New Thiazole Derivative Targeting Human Thymidylate Synthase

Carosati, Emanuele, Tochowicz, Anna, Marverti, Gaetano, Guaitoli, Giambattista, Benedetti, Paolo, Ferrari, Stefania, Stroud, Robert M., Finer-Moore, Janet, Luciani, Rosaria, Farina, Davide, Cruciani,

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 2.77 MB

english, 2012

26

LpxI structures reveal how a lipid A precursor is synthesized

Metzger, Louis E, Lee, John K, Finer-Moore, Janet S, Raetz, Christian R H, Stroud, Robert M

Journal:

Nature Structural and Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2012

27

Development and Binding Mode Assessment of N -[4-[2-Propyn-1-yl[(6 S )-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3 H -cyclopenta[ g ]quinazolin-6-yl]amino]benzoyl]- l -γ-glutamyl- d -glutamic Acid (BGC 945), a Novel Thymidylate Synthase Inhibitor That Targets Tumor Cells

Tochowicz, Anna, Dalziel, Sean, Eidam, Oliv, O’Connell, Joseph D., Griner, Sarah, Finer-Moore, Janet S., Stroud, Robert M.

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 3.64 MB

english, 2013

28

Acetylcholine Receptor Structure, Function, and Evolution

Stroud, Robert M., Finer-Moore, Janet

Journal:

Annual Review of Cell Biology

Année:

1985

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1985

29

LpxI: A Novel Phosphosaccharolipid Hydrolase

Metzger, Louis E., Lee, John K., Finer-Moore, Janet S., Raetz, Christian R.H., Stroud, Robert M.

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 35 KB

english, 2012

30

In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities

Czudnochowski, Nadine, Wang, Amy Liya, Finer-Moore, Janet, Stroud, Robert M.

Journal:

Journal of Molecular Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2013

31

[Part 1: Biological Sciences] || Amphipathic Analysis and Possible Formation of the Ion Channel in an Acetylcholine Receptor

Janet Finer-Moore and Robert M. Stroud

Journal:

Proceedings of the National Academy of Sciences

Année:

1984

Langue:

english

Fichier:

PDF, 840 KB

english, 1984

32

Pairwise specificity and sequential binding in enzyme catalysis: thymidylate synthase

Finer-Moore, Janet S., Montfort, William R., Stroud, Robert M.

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 1.21 MB

english, 1990

33

Mechanism-Based Inhibition of Thymidylate Synthase by 5-(Trifluoromethyl)-2'-deoxyuridine 5'-Monophosphate

Eckstein, Jens W., Foster, Paul G., Finer-Moore, Janet, Wataya, Yusuke, Santi, Daniel V.

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.76 MB

english, 1994

34

The pyrodelphonine chromophore. Crystal structures of pyrodelphinine and delphinine

Pelletier, S. William, Finer-Moore, Janet, Desai, Ranjit C., Mody, Naresh V., Desai, Haridutt K.

Journal:

Journal of Organic Chemistry

Année:

1982

Langue:

english

Fichier:

PDF, 1.52 MB

english, 1982

35

A Novel dCMP Methylase by Engineering Thymidylate Synthase †

Agarwalla, Sanjay, LaPorte, Sherry, Liu, Lu, Finer-Moore, Janet, Stroud, Robert M., Santi, Daniel V.

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 509 KB

english, 1997

36

Energetic Contributions of Four Arginines to Phosphate-Binding in Thymidylate Synthase Are More than Additive and Depend on Optimization of “Effective Charge Balance” †,‡

Morse, Richard J., Kawase, Shido, Santi, Daniel V., Finer-Moore, Janet, Stroud, Robert M.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 244 KB

english, 2000

37

Conformational Dynamics along an Enzymatic Reaction Pathway: Thymidylate Synthase, “the Movie” †

Stroud, Robert M., Finer-Moore, Janet S.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 376 KB

english, 2003

38

Asparagine 229 Mutants of Thymidylate Synthase Catalyze the Methylation of 3-Methyl-2‘-deoxyuridine 5‘-Monophosphate †

Costi, Paola M., Liu, Lu, Finer-Moore, Janet S., Stroud, Robert M., Santi, Daniel V.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 440 KB

english, 1996

39

Structural studies of .alpha.-bungarotoxin. 3. Corrections in the primary sequence and x-ray structure and characterization of an isotoxic .alpha.-bungarotoxin

Kosen, Phyllis Anne, Finer-Moore, Janet, McCarthy, Michael P., Basus, Vladimir J.

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 924 KB

english, 1988

40

The Role of Protein Dynamics in Thymidylate Synthase Catalysis: Variants of Conserved 2‘-Deoxyuridine 5‘-Monophosphate (dUMP)-Binding Tyr-261 †,‡

Newby, Zachary, Lee, Tom T., Morse, Richard J., Liu, Yaoquan, Liu, Lu, Venkatraman, Prasanna, Santi, Daniel V., Finer-Moore, Janet S., Stroud, Robert M.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2006

41

Structure of cuauchichicine. Its chemical correlation with (-)-".beta."-dihydrokaurene

Pelletier, S. William, Desai, Haridutt K., Finer-Moore, Janet, Mody, Naresh V.

Journal:

Journal of the American Chemical Society

Année:

1979

Langue:

english

Fichier:

PDF, 263 KB

english, 1979

42

Structural basis for recognition of polyglutamyl folates by thymidylate synthase

Kamb, Alexander, Finer-Moore, Janet, Calvert, A. Hilary, Stroud, Robert M.

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 2.15 MB

english, 1992

43

Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate

Montfort, William R., Perry, Kathy M., Fauman, Eric B., Finer-Moore, Janet S., Maley, Gladys F., Hardy, Larry, Maley, Frank, Stroud, Robert M.

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 5.01 MB

english, 1990

44

Episelection: Novel Ki .apprx. Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface

Katz, Bradley A., Finer-Moore, Janet, Mortezaei, Reza, Rich, Daniel H., Stroud, Robert M.

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 5.11 MB

english, 1995

45

Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate [Erratum to document cited in CA113(7):54978v]

Montfort, William R., Perry, Kathy M., Fauman, Eric B., Finer-Moore, Janet S., Maley, Gladys F., Hardy, Larry, Maley, Frank, Stroud, Robert M.

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 66 KB

english, 1990

46

Conformational analysis of the oxazolidine and tetrahydro-1,3-oxazine ring of C20-diterpenoid alkaloid derivatives

Pelletier, S. William, Mody, Naresh V., Desai, Haridutt K., Finer-Moore, Janet, Nowacki, Jacek, Joshi, Balawant S.

Journal:

Journal of Organic Chemistry

Année:

1983

Langue:

english

Fichier:

PDF, 2.20 MB

english, 1983

47

Tryptophan 80 and Leucine 143 Are Critical for the Hydride Transfer Step of Thymidylate Synthase by Controlling Active Site Access †,‡

Fritz, Timothy A., Liu, Lu, Finer-Moore, Janet S., Stroud, Robert M.

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 679 KB

english, 2002

48

D221 in Thymidylate Synthase Controls Conformation Change, and Thereby Opening of the Imidazolidine †,‡

Sage, Carleton R., Michelitsch, Melissa D., Stout, Thomas J., Biermann, Donna, Nissen, Robert, Finer-Moore, Janet, Stroud, Robert M.

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 260 KB

english, 1998

49

Cofactor triggers the conformational change in thymidylate synthase: implications for an ordered binding mechanism

Kamb, Alexander, Finer-Moore, Janet S., Stroud, Robert M.

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 2.02 MB

english, 1992

50

Mg 2+ Binds to the Surface of Thymidylate Synthase and Affects Hydride Transfer at the Interior Active Site

Wang, Zhen, Sapienza, Paul J., Abeysinghe, Thelma, Luzum, Calvin, Lee, Andrew L., Finer-Moore, Janet S., Stroud, Robert M., Kohen, Amnon

Journal:

Journal of the American Chemical Society

Année:

2013

Langue:

english

Fichier:

PDF, 2.99 MB

english, 2013